Publications

The link between oral health and systemic disease is well publicised in an academic field. However, not much research is done from an -omics perspective. Our lab looks to integrate health-care and -omic techniques in order to improve diagnostic and treatment services. We also look at patient perspectives to smooth treatment plans for patients and raise awareness of how looking after your teeth can prevent disease all over your body!

Highlighted

Patterns of subgingival microbiota in different periodontal phenotypes

L Nibali, V Sousa, M Davrandi, LS Liu, D Spratt, N Donos

Journal of Dentistry   ·   11 May 2016   ·   doi:10.1016/j.jdent.2021.103912

In order to investigate the bacterial microbiome in periodontal and peri-implant biofirms from aggressive periodontitis patients, 91 plaque samples were collected and analysed using 16S rRNA gene amplification and sequencing.

research collaboration

All

2024

Micro-Computed Tomography Analysis of Peri-Implant Bone Defects Exposed to a Peri-Implantitis Microcosm, with and without Bone Substitute, in a Rabbit Model: A Pilot Study

Camila Panes, Iván Valdivia-Gandur, Carlos Veuthey, Vanessa Sousa, Mariano del Sol, Víctor Beltrán

Bioengineering   ·   19 Apr 2024   ·   doi:10.3390/bioengineering11040397

2023

The efficacy of bone reconstructive therapies in the management of peri‐implantitis. A systematic review and meta‐analysis

Nikos Donos, Elena Calciolari, Mandeep Ghuman, Michela Baccini, Vanessa Sousa, Luigi Nibali

Journal of Clinical Periodontology   ·   13 Feb 2023   ·   doi:10.1111/jcpe.13775

2022

Oral Microcosm Biofilms Grown under Conditions Progressing from Peri-Implant Health, Peri-Implant Mucositis, and Peri-Implantitis

Vanessa Sousa, Dave Spratt, Mehmet Davrandi, Nikos Mardas, Víctor Beltrán, Nikolaos Donos

International Journal of Environmental Research and Public Health   ·   28 Oct 2022   ·   doi:10.3390/ijerph192114088

Biomarker Expression of Peri-Implantitis Lesions before and after Treatment: A Systematic Review

Haniyeh Moaven, Annesi Giacaman, Víctor Beltrán, Ye Han Sam, Daniel Betancur, Giuseppe Mainas, Seyed Ali Tarjomani, Nikolaos Donos, Vanessa Sousa

International Journal of Environmental Research and Public Health   ·   28 Oct 2022   ·   doi:10.3390/ijerph192114085

The Effect of Microcosm Biofilm Decontamination on Surface Topography, Chemistry, and Biocompatibility Dynamics of Implant Titanium Surfaces

Vanessa Sousa, Nikos Mardas, Dave Spratt, Iman A. Hassan, Nick J. Walters, Víctor Beltrán, Nikolaos Donos

International Journal of Molecular Sciences   ·   02 Sep 2022   ·   doi:10.3390/ijms231710033

High Prevalence of Periodontal Disease Observed in Patients on Hemodialysis: A Call for Equitable Access to Dental Care

Kajal Kotecha, Rebecca Ridout, Mira Shah, David W. Randall, Vanessa Sousa, Ravindra Rajakariar, Kieran McCafferty, Muhammad M. Yaqoob, Lochana Nanayakkara

Kidney International Reports   ·   01 Sep 2022   ·   doi:10.1016/j.ekir.2022.06.016

Molecular Biomarkers in Peri-Implant Health and Disease: A Cross-Sectional Pilot Study

Alejandra Chaparro, Víctor Beltrán, Daniel Betancur, Ye-Han Sam, Haniyeh Moaven, Ali Tarjomani, Nikolaos Donos, Vanessa Sousa

International Journal of Molecular Sciences   ·   29 Aug 2022   ·   doi:10.3390/ijms23179802

Histological and Immunohistochemical Analysis of Peri-Implant Soft and Hard Tissues in Patients with Peri-Implantitis

Valentina Flores, Bernardo Venegas, Wendy Donoso, Camilo Ulloa, Alejandra Chaparro, Vanessa Sousa, Víctor Beltrán

International Journal of Environmental Research and Public Health   ·   08 Jul 2022   ·   doi:doi.org/10.3390/ijerph19148388

Histological and Immunohistochemical Analysis of Peri-Implant Soft and Hard Tissues in Patients with Peri-Implantitis

Valentina Flores, Bernardo Venegas, Wendy Donoso, Camilo Ulloa, Alejandra Chaparro, Vanessa Sousa, Víctor Beltrán

International Journal of Environmental Research and Public Health   ·   08 Jul 2022   ·   doi:10.3390/ijerph19148388

Public involvement in research: exploring periodontal and peri-implant health and disease in partnership with Perio@RLH patient forum members

Vanessa Sousa, Haniyeh Moaven, Amieth Yogarajah, Daniel Betancur, Víctor Beltrán, Nara Lara-Pompa, Lochana Nanayakkara, Nikolaos Donos

British Dental Journal   ·   25 Mar 2022   ·   doi:10.1038/s41415-022-3989-0

Salivary Microbial Dysbiosis Is Associated With Peri-Implantitis: A Case-Control Study in a Brazilian Population

Debora Pallos, Vanessa Sousa, Magda Feres, Belen Retamal-Valdes, Tsute Chen, ..., Gabriela Schwab, Lucas Augusto Moyses Franco, Ester Cerdeira Sabino, Paulo Henrique Braz-Silva, Jamil Awad Shibli

Frontiers in Cellular and Infection Microbiology   ·   05 Jan 2022   ·   doi:10.3389/fcimb.2021.696432

2021

Collagen Quantification in Peri-implant Soft Tissues in Human Peri-Implantitis Lesions

Valentina Flores, Bernardo Venegas, Wendy Donoso, Camilo Ulloa, Alejandra Chaparro, Vanessa Sousa, Víctor Beltrán

International Journal of Morphology   ·   01 Jun 2021   ·   doi:10.4067/S0717-95022021000300683

2020

In situ endoscopic analysis of bone microstructure and vascularization in the post-explantation cavities from patients diagnosed with advanced peri-implantitis lesions: A preliminary report.

Víctor Beltrán, Pablo Acuña-Mardones, Vanessa Sousa

Journal of Oral Research   ·   22 Sep 2020   ·   doi:10.17126/JORALRES.2020.025

Differences in the periodontal microbiome of successfully treated and persistent aggressive periodontitis

Luigi Nibali, Vanessa Sousa, Mehmet Davrandi, David Spratt, Qumasha Alyahya, Jose Dopico, Nikos Donos

Journal of Clinical Periodontology   ·   26 Jun 2020   ·   doi:10.1111/jcpe.13330

2019

In Situ Endoscopic Analysis of Vascular Supply and Regenerated Alveolar Bone in β-TCP Grafted and Ungrafted Postextraction Sites before Implant Placement: A Prospective Case Control Study

Víctor Beltrán, Marcio Lazzarini, Rodolfo Figueroa, Vanessa Sousa, Wilfried Engelke

BioMed Research International   ·   06 Nov 2019   ·   doi:10.1155/2019/2797210

2016

Peri‐implant and periodontal microbiome diversity in aggressive periodontitis patients: a pilot study

Vanessa Sousa, Luigi Nibali, David Spratt, Jose Dopico, Nikos Mardas, Aviva Petrie, Nikolaos Donos

Clinical Oral Implants Research   ·   11 May 2016   ·   doi:10.1111/clr.12834

Patterns of subgingival microbiota in different periodontal phenotypes

L Nibali, V Sousa, M Davrandi, LS Liu, D Spratt, N Donos

Journal of Dentistry   ·   11 May 2016   ·   doi:10.1016/j.jdent.2021.103912

In order to investigate the bacterial microbiome in periodontal and peri-implant biofirms from aggressive periodontitis patients, 91 plaque samples were collected and analysed using 16S rRNA gene amplification and sequencing.

research collaboration

Experimental models for contamination of titanium surfaces and disinfection protocols

Vanessa Sousa, Nikos Mardas, David Spratt, David Boniface, Michel Dard, Nikolaos Donos

Clinical Oral Implants Research   ·   10 Feb 2016   ·   doi:10.1111/clr.12735

An in vitro study on disinfection of titanium surfaces

Arifo Widodo, David Spratt, Vanessa Sousa, Aviva Petrie, Nikolaos Donos

Clinical Oral Implants Research   ·   10 Feb 2016   ·   doi:10.1111/clr.12733

2015

A systematic review of implant outcomes in treated periodontitis patients

Vanessa Sousa, Nikos Mardas, Bruna Farias, Aviva Petrie, Ian Needleman, David Spratt, Nikolaos Donos

Clinical Oral Implants Research   ·   18 Sep 2015   ·   doi:10.1111/clr.12684